C Neural tube defects are associated with high levels of Acetylcholinesterase. Ref: Genetic disorders and Fetus, 4th Edition, Page 673; lan Donald's Practical Obstetric Problem By Renu Misra, 6th Edition, Page 44 * In intra embryonic life, neural tube is open at both end and freely communicate with amniotic cavity. Failure of closure of neural tube results in persistent of this communication. This allows excretion of following fetal substances into amniotic cavity ? Alpha - fetoprotein - Acetylcholinesterase * These serve as biochemical markers for NTDs.
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